toronto human knockout pooled library tkov3 (Addgene inc)
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toronto human knockout pooled library tkov3
Toronto Human Knockout Pooled Library Tkov3, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 92 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/toronto+human+knockout+pooled+library+tko/Toronto+KnockOut+(TKO)+CRISPR+Library+-+Version+3+(Pooled+Libraries+%2390294%2C+%23125517)/bio_rxiv__64898__2026__02__04__703735-141-1-7
Average 94 stars, based on 92 article reviews
Toronto Human Knockout Pooled Library Tkov3, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 92 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/toronto+human+knockout+pooled+library+tko/Toronto+KnockOut+(TKO)+CRISPR+Library+-+Version+3+(Pooled+Libraries+%2390294%2C+%23125517)/bio_rxiv__64898__2026__02__04__703735-141-1-7
Average 94 stars, based on 92 article reviews
toronto human knockout pooled library tkov3 - by Bioz Stars,
2026-09
94/100 stars
Images
1) Product Images from "BAG6 and RNF126 are broadly involved in protein quality control of non-native missense protein variants"
Article Title: BAG6 and RNF126 are broadly involved in protein quality control of non-native missense protein variants
Journal: bioRxiv
doi: 10.64898/2026.02.04.703735
Figure Legend Snippet: (A) Schematic representation of the screening protocol. HEK293T cells expressing GFP-Parkin R42P from the landing pad were transduced with the TKOv3 sgRNA library. Fluorescence activated cells sorting (FACS) was used to collect the cells with the 5% highest and lowest GFP:mCherry ratios. Finally, the sgRNAs were identified by sequencing. Created in BioRender. Hartmann-Petersen, R. (2025) https://BioRender.com/mxx8owh . (B) Plot displaying sgRNA enrichment in the 5% highest GFP:mCherry bin. Significant (p < 0.001 and log2 fold change > 0.5) hits are colored red. Control sgRNAs are marked in green. (C) Plot displaying sgRNA enrichment in the 5% lowest GFP:mCherry bin. Significant (p < 0.001 and log2 fold change > 0.5) hits are colored red. Control sgRNAs are marked in green.
Techniques Used: Expressing, Transduction, Fluorescence, Sequencing, Control
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